This is the junction between two neurons. At the one end you have the pre-synaptic membrane - the terminal end of the previous neuron, the pre-synaptic neuron - and on the other side you have the post-synaptic membrane, part of the post-synaptic neuron. Action potentials typically cross the cleft by the use of neurotransmitters. Examples include ACh (Acetyl Choline), often used in the synaptic clefts of parasympathetic neurons.
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