The 1981 Datsun 720 4-wheel drive pickup with a Z22 engine and standard transmission typically has an estimated fuel economy of around 18 to 22 miles per gallon (mpg), depending on driving conditions and maintenance. However, actual mileage can vary based on factors such as load, terrain, and driving habits. For the most accurate information, it's best to consult the owner's manual or check with vintage vehicle enthusiasts.
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