You are a federal inmate in SC who wants a divorce from your wife in NC?

Just wait until you get out, or if she wants it too it'd be a whole lot easier for her to file for it since she's not stuck in jail. ADDED: I notice that your question doesn't mention that SHE wants a divorce from you. Although it would probably be easier for her to file for divorce in NC (if she even wants one) it IS possible for you to do it 'Pro Se' while in federal custody in SC (It's a little more difficult - But HEY, you've got nothing but time, right?). If she wishes to contest your request for divorce and if the two of you have any children it could really open a can of worms. If you have access to any legal aid while in prison see if you can get an appointment to talk with them. You aren't the first person to ever get divorced while in jail, so, it CAN be done.