Can you take Vicodin and Cyclobenzaprine together?

it depends, if its nyquill, then probley not a good idea ===ANOTHER ANSWER=== VICODIN (hydrocodone) is an anelgisic [pain killer]. But is also prescibed for cough. If the cough syrup in question is an over-the-counter tussin DM, then it's probably o.k. if taken in moderation. HOWEVER, you really should ask your doctor or any pharmacist (Rph). If it is prescription cough syrup, then you should be extra careful and certainly ask a pharmacist.