What are B and T cells called that have not yet been exposed to an antigen?

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2026-05-06 23:35

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B and T cells that have not yet been exposed to an antigen are referred to as "naive" cells. These cells are mature but have not yet encountered their specific antigen, which is necessary for their activation and differentiation into effector cells. Naive B cells can produce antibodies, while naive T cells can become cytotoxic T cells or helper T cells upon activation.

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