Can Diphenhydramine Cause Erectile Dysfunction If used For a long period of time?

Yes, long-term use of diphenhydramine, an antihistamine, can potentially lead to erectile dysfunction in some individuals. This is primarily due to its anticholinergic properties, which can affect nerve signaling and blood flow. Additionally, prolonged use may impact hormonal levels or contribute to other health issues that can interfere with sexual function. It's important to consult a healthcare professional if experiencing such side effects.