What are the Negative consequences of mismatching calorie intake with physical activity?

Im not exactly sure what you mean, but the forever standing equation of weight loss weight gain is : Calorie intake - Physical activity = weight loss or weight gain. The more calories you consume the more weight you will gain. one pound of fat equals 3500 calories. If your goal is to loose weight, you can figure out how many calories your body needs from a calorie counter website such as Livestrong.com where you can record your weight and daily exercise and it will give you the amount of calories needed to loose weight, gain weight and/ or sustain your current weight. 75-80 % of weight loss is calorie intake and 20-25% is exercise.