What are the different research methods used by Dr Sayer for his patients in the movie awakenings?

Dr. Sayer in the movie "Awakenings" primarily uses observational research methods, carefully documenting the behaviors and responses of his patients to treatments. He also incorporates experimental research methods by testing different medications and therapies to try to awaken his patients from their catatonic state. Additionally, he consults with other medical professionals and reviews existing literature to inform his treatment approach.