Does taking estrogen lower testosterone

Yes, taking estrogen can lower testosterone levels in individuals assigned male at birth. Estrogen can lead to decreased testosterone production by suppressing the hypothalamic-pituitary-gonadal (HPG) axis, which regulates hormone production. Additionally, estrogen may promote the conversion of testosterone to estradiol via aromatase, further reducing testosterone levels in the body. However, the extent of this effect can vary depending on dosage and individual physiology.