Dendrotoxin, a neurotoxin found in certain snake venoms, inhibits voltage-gated potassium channels, specifically the K+ channels. By blocking these channels, dendrotoxin prolongs the action potential duration and enhances neurotransmitter release at the synapse. This alteration can lead to increased neuronal excitability and disrupt normal signaling, potentially resulting in excessive neuronal firing or excitotoxicity. Overall, dendrotoxin significantly impacts the signaling capability of a neuron by modifying its electrical properties.
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