Can lotion penetrate 7 layers of skin?

Lotion typically does not penetrate all seven layers of skin, as the outermost layer, the stratum corneum, acts as a barrier to protect against moisture loss and external substances. While some ingredients in lotions can reach deeper layers, most topical products primarily affect only the upper layers of the skin. Certain formulations, especially those containing specific active ingredients or using advanced delivery systems, may enhance penetration, but complete absorption through all skin layers is generally limited.