What are the differences between the 5' end and the 3' end of a DNA strand?

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2026-07-12 05:21

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The 5' end of a DNA strand has a phosphate group attached to the 5th carbon of the sugar molecule, while the 3' end has a hydroxyl group attached to the 3rd carbon. This creates a directionality in the DNA molecule, with the 5' end being the starting point for DNA synthesis and the 3' end being the ending point.

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