Which parent carries ALPS?

Autoimmune Lymphoproliferative Syndrome (ALPS) is primarily inherited in an autosomal dominant pattern, meaning that an affected individual has a 50% chance of passing the mutated gene to each child, regardless of whether the parent is the mother or the father. Typically, the condition is linked to mutations in genes involved in the apoptosis pathway, such as FAS. Therefore, either parent can carry and pass on the genetic mutation associated with ALPS.