Why does tobacco mosaic virus infect only tobacco cells and not human cells?

Tobacco mosaic virus (TMV) specifically infects tobacco and other related plant cells because it recognizes and binds to specific receptors on the surface of these plant cells, which are not present in human cells. The virus's structure and replication mechanisms are adapted to the cellular machinery of plants, allowing it to hijack their processes for reproduction. In contrast, human cells lack the necessary components for TMV to attach, enter, and replicate, making them resistant to this virus.