Can you make a daycare in the sims 2 open for business?

Sadly, no. The sims2 PC Open For Buisness allows you to sell ojbects with your own buisness, although it should allow you to because a daycare is a service, it does not. You can only sell items with this exspansion pack. You will have to purchase the Sims2 PC Freetime if you were looking to open a daycare. I hope I helped! Thanks :D