Can the stage of bradyzoites that form cysts within host cells allow bradyzoites to destroy host tissue and cause disease?

Bradyzoites, the dormant stage of the parasitic protozoan Toxoplasma gondii, typically form cysts within host cells, allowing them to evade the host's immune response. While they are primarily associated with chronic infection rather than acute tissue destruction, the presence of these cysts can lead to inflammation and damage to host tissues, especially if the immune system is compromised or if cysts rupture. In some cases, the immune response to these cysts can also contribute to tissue damage, resulting in disease symptoms. Therefore, while bradyzoites themselves do not directly destroy tissue, their presence and the resultant immune response can contribute to disease pathology.