How the buffer respond to acid and base compared to the liver?

Buffer systems in the body help maintain pH stability by absorbing excess acid or base to keep the body's pH within a narrow range. The liver plays a key role in maintaining acid-base balance by producing and excreting bicarbonate ions to help neutralize excess acid in the bloodstream. Buffer systems in the blood, such as bicarbonate/carbonic acid and protein buffers, work alongside the liver to regulate pH levels throughout the body.