Can Benadryl cause palpitations

Yes, Benadryl (diphenhydramine) can cause palpitations as a side effect. This antihistamine may lead to increased heart rate or irregular heartbeat, particularly in sensitive individuals or when taken in higher doses. Additionally, its sedative effects can sometimes mask underlying anxiety or other conditions that contribute to palpitations. If you experience palpitations after taking Benadryl, it’s advisable to consult a healthcare professional.