What does He shall spurn fate mean in the story of Macbeth?

"He shall spurn fate" in the story of Macbeth refers to Macbeth's belief that he is invincible and can overcome destiny or fate. This phrase reveals his arrogance and disregard for the eventual repercussions of his actions, leading to his downfall. Ultimately, Macbeth's actions go against the natural order, resulting in tragedy.