Why do males and females express X-linked alleles differently?

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2026-05-06 15:15

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X-linked recessive traits that are not related to feminine body characteristics are primarily expressed in the observable characteristics, or phenotype of men. This is due to the fact that men only have one X chromosome. Subsequently, genes on that chromosome not coding for gender are usually expressed in the male phenotype even if they are recessive since there are no corresponding genes on the Y chromosome in most cases. In women, a recessive allele on one X chromosome is often masked in their phenotype by a dominant normal allele on the other. This explains why women are frequently carriers of X-linked traits but more rarely have them expressed in their own phenotypes.

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