Most water reabsorption in the kidney tubule occurs in the proximal convoluted tubule (PCT), where approximately 65-70% of filtered water is reabsorbed. This process is primarily driven by osmotic gradients created by the reabsorption of solutes, particularly sodium. Additional reabsorption occurs in the loop of Henle and the collecting ducts, but the PCT is the main site for water recovery in the nephron.
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