What is the normal level of anti-nuclear antibody?

The normal level of anti-nuclear antibodies (ANAs) is typically considered to be negative or very low, often defined as a titer of 1:40 or lower in most laboratories. However, a small percentage of healthy individuals may have low levels of ANAs without any autoimmune disease. Higher levels or specific patterns of ANAs can indicate autoimmune disorders such as lupus or rheumatoid Arthritis. It's important to interpret ANA test results in conjunction with clinical symptoms and other diagnostic tests.