How does the reduction of FAD plus to FADH occur?

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2026-04-20 06:25

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The reduction of FAD (flavin adenine dinucleotide) to FADH occurs when FAD accepts two electrons and two protons (H+) during a biochemical reaction, typically in metabolic processes like the citric acid cycle. This process is facilitated by enzymes known as dehydrogenases, which catalyze the transfer of electrons from substrates to FAD. The addition of electrons and protons transforms FAD into its reduced form, FADH, which can then participate in further metabolic reactions, particularly in the electron transport chain to produce ATP.

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