What is the best route from Portland Maine to cape may New Jersey?

The best route from Portland, Maine to Cape May, New Jersey typically involves taking I-95 South. You would travel through New Hampshire and Massachusetts, then merge onto I-295 South in Rhode Island, and eventually connect to I-95 South again towards New York City. After navigating through New York, you can take the Garden State Parkway South, which leads directly to Cape May. The total drive is about 6-7 hours, depending on traffic and road conditions.