What does cefoxitin inhibit?

Cefoxitin is a cephalosporin antibiotic that primarily inhibits bacterial cell wall synthesis. It accomplishes this by binding to penicillin-binding proteins (PBPs), which are essential for the cross-linking of peptidoglycan layers in the bacterial cell wall. This inhibition disrupts the integrity of the cell wall, leading to cell lysis and death, particularly in gram-negative bacteria. Cefoxitin is also effective against some anaerobic bacteria.