Is It always possible to make requests to multiple websites with different domain names from an Ajax client script?

No, it's not always possible to make requests to multiple websites with different domain names from an Ajax client script due to the Same-Origin Policy implemented by Web Browsers. This policy restricts web pages from making requests to a different domain than the one that served the web page. However, developers can use techniques like Cross-Origin Resource Sharing (CORS) or JSONP to enable such cross-domain requests when the target server allows it.