When sister chromatids fail to separate properly durng which phase is this problem most likely to occur?

Sister chromatids are most likely to fail to separate properly during anaphase of mitosis or meiOSis. This failure, known as nondisjunction, can lead to an unequal distribution of chromosomes to the daughter cells. It can result in conditions such as aneuploidy, where cells have an abnormal number of chromosomes. Proper checkpoint mechanisms typically monitor and ensure correct chromosome separation during these phases.