To replace an interior door handle on a 2000 Cadillac Escalade, start by removing the door panel. Use a flathead screwdriver to pry off any plastic covers and then unscrew the panel using a socket wrench. Once the panel is off, locate the handle mechanism, disconnect any rods or clips, and remove the old handle. Install the new handle by reversing the process, ensuring all connections are secure before reattaching the door panel.
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