When working with a highly reactive material what is the main safety precaution that should be taken?

When working with highly reactive materials, the primary safety precaution is to ensure proper containment and ventilation. This includes using appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats, as well as working in a fume hood or well-ventilated area to prevent exposure to harmful fumes or reactions. Additionally, having emergency equipment, like eyewash stations and safety showers, readily accessible is crucial. Always follow established protocols and have a clear understanding of the material's properties and potential hazards.