What are the neurotransmitter released by the neuromuscular junction resulting in depolarization?

The primary neurotransmitter released at the neuromuscular junction is acetylcholine (ACh). When a motor neuron releases ACh, it binds to receptors on the muscle cell membrane, leading to depolarization of the muscle fiber. This depolarization initiates an action potential, resulting in muscle contraction. Additionally, the enzyme acetylcholinesterase breaks down ACh in the synaptic cleft to terminate the signal.