What drugs cannot be taken with Topamax?

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2026-05-07 21:06

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The following list may not be complete. Please check with your health care provider or pharmacist for all drug interations..

  • glycopyrrolate (Robinul);

  • lithium (Eskalith, LithoBid);

  • hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic);

  • mepenzolate (Cantil);

  • metformin (Glucophage, Actoplus Met, Avandamet, Fortamet, Janumet, PrandiMet, Riomet);

  • atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

  • bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);

  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

  • glaucoma medications such as acetazolamide (Diamox) or methazolamide (Neptazane);

  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro-Banthine); or

  • other seizure medications such as carbamazepine (Carbatrol, Tegretol), lamotrigine (Lamictal), phenytoin (Dilantin), valproic acid (Depakote, Depakene), or zonisamide (Zonegran).

  • Also avoid Ketogenic diets (such as Atkins, etc.) that have you increase your protein intake and limit the carbs you eat as this can cause kidney stones.

  • Drink plenty of fluids while taking this drug as it can cause you to become dehydrated easilly.

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