Has the National government abused its powers in its relations with the states?

Absolutely. In almost every aspect. For example: The interstate commerce clause is used as a catch-all for almost any legislation the federal government wants to enact. Take the Bureau of Alcohol Tobacco and Firearms. They are granted their powers from the interstate commerce clause. The reasoning is that guns are bought and sold in interstate commerce. So, If this is a good reason to form an entire beurocratic entity, why do we not have a Bureau of Apples, Tennis Rackets, and Doorknobs? After all, aren't these things also sold interstate? Why is there justification for one because of the "catch-all" of interstate commerce, but not any other item that is also sold interstate? Just one of hundreds of examples of the federal government abusing It's powers.