There are actually several real-life conditions and diseases that cause one to act in a zombie-like state.
They are:
permanent neurological damage - sometimes locking people in a zombie state.
There are several fictional conditions that people believe can cause zombification, such as "Ataxic Neurodegenerative Satiety Deficiency Syndrome", which was made up by an author for a spoof medical journal - it does not exist in real life.
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