How much pressure in autoclave when 121 centigrade?

In an autoclave operating at 121 degrees Celsius, the pressure typically reaches about 15 pounds per square inch (psi), which is approximately 1.05 bar or 103 kPa. This pressure is necessary to effectively sterilize equipment and materials by raising the boiling point of water, allowing for the destruction of microorganisms. The combination of temperature and pressure ensures effective sterilization during the autoclaving process.