This is a controversial question as different branches of Christianity will give you different answers.
Protestant and Orthodox churches generally think he had half-brothers and sisters while Catholics do not.
There are various passages in The Bible that mention siblings. For example:
Matthew 13:55-56: "Is this not the carpenter's son? Is not His mother called Mary? And His brothers James, Joses, Simon, and Judas? And His sisters, are they not all with us?"
Such passages are interpreted according to the dogma of the church involved.
Answer/
Six brothers and two sisters. Justus/Joseph, Simeon, James and Joses/Judas, step or half brothers, Assia and Lydia, step or half sisters - The History of Joseph the Carpenter; James son of Zebedee(Theuda), milk-kin brother - James' Apocalypse, John son of Zebedee, foster brother - John 19:26/27.
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