When did the colonists in Jamestown face hard times?

The colonists in Jamestown faced significant hardships during the winter of 1609-1610, a period known as the "Starving Time." Severe food shortages, compounded by poor relations with local Native American tribes and harsh weather conditions, led to widespread hunger and suffering. By the spring of 1610, only about 60 of the original 500 colonists had survived. The challenges faced during this time nearly led to the abandonment of the settlement.