In osteoarthritis, hyaline cartilage undergoes degeneration and becomes progressively damaged due to mechanical stress and inflammation. This leads to the breakdown of the cartilage matrix, causing it to lose its elasticity and cushioning properties. As the cartilage erodes, it can result in increased friction between bones, leading to pain, stiffness, and reduced joint mobility. Over time, the underlying bone may also become affected, leading to further joint complications.
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