Can you get sick by mixing liquor and beer and and wine?

Pass - but I can tell you it makes the mother of hangovers Here in the UK we generally say don't mix the grape and the grain - so beer and whiskey is OK, wine and brandy is OK. It's mostly myth and folklore claiming that you'd get more hungover if you're mixing your alcohols. Far more important is the total amount, and going from one drink to another makes it harder to keep track of how much you're actually drinking.