When not to use ipratropium?

Ipratropium should not be used in patients with a known hypersensitivity to the drug or its components, including atropine and its derivatives. It is also contraindicated in individuals with narrow-angle glaucoma, prostatic hypertrophy, or bladder neck obstruction, as it may exacerbate these conditions. Additionally, caution should be exercised when prescribing ipratropium to patients with certain cardiovascular conditions, as it may cause adverse effects.