What are simple and complex enzymes?

Simple enzymes are proteins that consist solely of amino acids and catalyze biochemical reactions without any additional components. Complex enzymes, on the other hand, are made up of a protein portion (the apoenzyme) and a non-protein component, such as a cofactor or coenzyme, which is necessary for their activity. The presence of these additional components often enhances the enzyme's catalytic efficiency and specificity. Examples of cofactors include metal ions, while coenzymes are typically organic molecules derived from vitamins.