What is sma 18?

SMA 18, or Spinal Muscular Atrophy type 18, is a rare genetic disorder characterized by progressive muscle weakness and atrophy due to the degeneration of motor neurons in the spinal cord and brainstem. It is caused by mutations in the SMN1 gene, which is crucial for the survival of these motor neurons. SMA 18 is one of the later-onset forms of the disease and typically manifests in adolescence or adulthood. Treatment options may include gene therapy and supportive care to manage symptoms and improve quality of life.