Is resin hazardous

Generally no. Tree sap is a resin (e.g. maple syrup is extracted from maple tree sap and we use this as food, natural rubber latex comes from the rubber tree sap and is used to make latex gloves and other items). Plastics and epoxy glues are resins and we use them for nearly everything.

Some types of resin are used to separate contaminants from liquids and these might become hazardous during that process, depending on the contaminants.