What is the difference between NSAIDs in terms of their selectivity for COX-1 and COX-2 enzymes?

Nonsteroidal anti-inflammatory drugs (NSAIDs) differ in their selectivity for COX-1 and COX-2 enzymes. COX-1 is involved in protecting the stomach lining and maintaining kidney function, while COX-2 is involved in inflammation and pain. Some NSAIDs are non-selective, meaning they inhibit both COX-1 and COX-2, while others are selective for COX-2, which may reduce the risk of stomach ulcers and kidney damage.