How is cerebral perfusion pressure calculated?

Cerebral perfusion pressure (CPP) is calculated using the formula: CPP = Mean Arterial Pressure (MAP) - Intracranial Pressure (ICP). Mean Arterial Pressure is typically estimated using the formula MAP = (SBP + 2 * DBP) / 3, where SBP is systolic blood pressure and DBP is diastolic blood pressure. By subtracting the intracranial pressure from the mean arterial pressure, CPP provides an indication of the pressure gradient driving blood flow to the brain. Maintaining adequate CPP is crucial for ensuring sufficient cerebral blood flow and oxygen delivery.