What are the three major reasons for conflict in the middle east?

1) The power struggle and animosity between Sunni and Shiite Muslims, 2) the establishment and later support by the West of the State of Israel on what Arabs consider to be Arab soil; and 3) the emerging of the Islamic State (IS) - thanks to the US invasion of Iraq, which disenfrenchised Iraq's top military men who then went on to start and lead IS.