What protein deos trisomy 21 code for?

Trisomy 21, also known as Down syndrome, is caused by an extra copy of chromosome 21, which leads to the overexpression of several genes located on that chromosome. One of the key proteins coded by genes on chromosome 21 is amyloid precursor protein (APP), which is implicated in the development of Alzheimer's disease. Other important proteins include superoxide dismutase 1 (SOD1) and collagen type IV alpha 1 chain (COL4A1), both of which play roles in cellular processes and structural integrity. The overproduction of these proteins contributes to the diverse phenotypic features associated with Down syndrome.