Why don't you cough up mucus with end stage emphysema?

In end-stage emphysema, the damage to the lungs results in the destruction of alveoli and reduced surface area for gas exchange, which can lead to a significant decrease in mucus production. Additionally, the airway inflammation and obstruction may impair the body’s ability to clear mucus effectively. As a result, individuals may experience less productive coughing and reduced mucus expectoration despite the chronic lung condition. This stage can also lead to complications that further diminish the body's natural mucus production and clearance mechanisms.