The "nature vs. nurture" debate suggests that either genetics ("nature") or the environment ("nurture'') played a major role in producing particular behaviors, personality traits, psychological disorders, or pretty much any other thing that a human does. The emerging picture from current research is that both nurture and nature play a role in directing behavior, and the focus has shifted to examining the relative contributions of each influence rather than the absolute contributions of either influence alone. In short, it's the interaction of genes and environmental influences that determines what humans do.
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