What are some important events in history that happpened in the 16th century?

The 16th century was marked by several significant events, including the Protestant Reformation, which began in 1517 when Martin Luther posted his Ninety-Five Theses, challenging the Catholic Church's practices. The Age of Exploration also flourished during this time, with explorers like Ferdinand Magellan and Sir Francis Drake expanding European knowledge of the world and establishing overseas empires. Additionally, the Spanish conquest of the Aztec and Inca empires transformed the Americas, leading to profound cultural and demographic changes. These events collectively reshaped religious, political, and social landscapes in Europe and beyond.