Sloughing off the endometrium refers to the process where the uterine lining, or endometrium, sheds during menstruation. This occurs when hormonal changes signal the end of the menstrual cycle, leading to the breakdown and expulsion of the thickened lining that had prepared for a potential pregnancy. The shedding results in menstrual bleeding, typically lasting a few days. This process is a normal part of the female reproductive cycle.
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